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Kelvin Owusu MD > Blog > Featured Article > Intermittent Fasting: A Dietitian’s Perspective
Featured ArticleWellness 360

Intermittent Fasting: A Dietitian’s Perspective

Sarah Salomey Okine
Last updated: March 12, 2025 9:45 am
Sarah Salomey Okine Published March 12, 2025
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Intermittent fasting (IF) has surged in popularity over the past decade, touted as a powerful tool for weight loss, metabolic health, and even longevity. As a dietitian, I’m often asked whether this eating pattern lives up to the hype or if it’s just another passing trend. The truth, as with most things in nutrition, lies in the nuance.

Contents
Based on current research, intermittent fasting offers both promising benefits and notable risks. Let’s break it down.What Is Intermittent Fasting?The Good: Evidence-Based Benefits1. Weight Loss and Fat Reduction2. Improved Insulin Sensitivity3. Cellular Repair and Longevity (maybe)4. Heart HealthThe Bad: Potential Downsides and Risks1. Hunger, Fatigue, and Irritability2. Muscle Loss Risk3. Nutrient Deficiencies4. Not Ideal for EveryoneThe Dietitian’s Take: A Balanced ApproachHowever, it’s not inherently superior to other eating patterns. A 2021 study in The New England Journal of Medicine compared IF to daily calorie restriction and found no significant difference in weight loss or metabolic outcomes after a year. This tells us that consistency and individual preference matter more than the method itself. Practical Tips for Success The Bottom Line
Based on current research, intermittent fasting offers both promising benefits and notable risks. Let’s break it down.

What Is Intermittent Fasting?

Intermittent fasting isn’t a diet in the traditional sense it’s an eating pattern that alternates periods of eating with periods of fasting. Common methods include the 16:8 approach (16 hours of fasting, 8 hours of eating), the 5:2 methods (eating normally for 5 days and restricting calories to 500–600 on 2 nonconsecutive days), and alternate-day fasting. Unlike conventional diets that focus on WHAT you eat, IF centers on WHEN you eat, making it appealing for its simplicity.

The Good: Evidence-Based Benefits

Research highlights several potential benefits of intermittent fasting, particularly when done thoughtfully.

1. Weight Loss and Fat Reduction

Studies consistently show that IF can be an effective strategy for weight loss. A 2019 systematic review in Obesity Reviews found that IF led to significant reductions in body weight, typically 3–8% over 8–12 weeks comparable to traditional calorie restriction.

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The mechanism? Fasting reduces overall calorie intake (assuming no overcompensation during eating windows) and may enhance fat oxidation by tapping into stored energy reserves during fasting periods.

2. Improved Insulin Sensitivity

IF may benefit metabolic health by improving insulin sensitivity, a key factor in preventing type 2 diabetes. A 2021 study in The Journal of Clinical Endocrinology & Metabolism demonstrated that alternate-day fasting lowered fasting insulin levels and improved insulin response in adults with obesity. This is likely due to reduced glucose availability during fasting, which prompts the body to become more efficient at utilizing insulin.

3. Cellular Repair and Longevity (maybe)

One of the most intriguing claims about IF is its potential to promote autophagy; a cellular “clean-up” process where damaged components are removed. Animal studies, like those published in Nature Reviews Molecular Cell Biology (2020), suggest fasting triggers autophagy, which might slow aging. However, human data is less conclusive, and we’re still piecing together whether this translates to meaningful longevity benefits, hence the ‘maybe’.

4. Heart Health

Some evidence links IF to cardiovascular improvements. A 2022 meta-analysis in The American Journal of Clinical Nutrition found that IF reduced LDL cholesterol, triglycerides, and blood pressure in certain populations. These changes could lower the risk of heart disease; though long-term studies are needed to confirm this.

The Bad: Potential Downsides and Risks

While the benefits are compelling, intermittent fasting isn’t a one-size-fits-all solution. Research and clinical experience reveal several drawbacks to consider.

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1. Hunger, Fatigue, and Irritability

Fasting isn’t easy for everyone. A 2020 study in Nutrients reported that participants on IF regimens often experienced increased hunger, fatigue, and mood disturbances, especially in the early stages. For some, this can derail adherence and negatively impact quality of life, hardly a win for sustainable health.

2. Muscle Loss Risk

Weight loss from IF isn’t always fat-specific. A 2016 study in JAMA Internal Medicine found that prolonged fasting without adequate protein intake during eating windows could lead to muscle breakdown alongside fat loss. For older adults or those with low physical activity, this could compromise strength and mobility over time.

3. Nutrient Deficiencies

Shortened eating windows can make it harder to meet nutrient needs. Research in The British Journal of Nutrition (2021) noted that IF participants sometimes fell short on vitamins like D and B12, minerals like calcium, and fiber especially if they leaned on convenience foods rather than balanced meals. As a dietitian, I see this as a red flag for long-term health.

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4. Not Ideal for Everyone

IF can backfire for certain groups. Pregnant or breastfeeding women, individuals with a history of eating disorders, and those with conditions like diabetes (requiring medication timing with meals) may face risks. A 2023 review in Diabetes Care warned that fasting could lead to hypoglycemia in poorly managed diabetes, underscoring the need for medical supervision.

The Dietitian’s Take: A Balanced Approach

So, is intermittent fasting worth trying? It depends. Research suggests it’s a viable option for weight loss and metabolic health in healthy adults who can adapt to the schedule. Pairing IF with nutrient-dense foods like lean proteins, whole grains, fruits, vegetables, and healthy fats maximizes health benefits and minimizes risks. Resistance training during IF can also help preserve muscle mass, addressing one of its key pitfalls.

However, it’s not inherently superior to other eating patterns. A 2021 study in The New England Journal of Medicine compared IF to daily calorie restriction and found no significant difference in weight loss or metabolic outcomes after a year. This tells us that consistency and individual preference matter more than the method itself.
 Practical Tips for Success

If you’re considering IF, here’s my advice as a dietitian:

– Start Gradually: Ease into it with a 12:12 schedule before jumping to 16:8.

– Prioritize Protein and Fiber: Break your fast with balanced meals to support satiety and nutrition.

– Stay Hydrated: Water, herbal tea, and black coffee coconut water are your fasting friends.

– Listen to Your Body: If you feel unwell or overly hungry, adjust or stop. Health isn’t one-size-fits-all.

– Consult a Professional: Work with a dietitian or doctor, especially if you have underlying conditions.

 The Bottom Line

Intermittent fasting isn’t a magic bullet, but it’s not a fad to dismiss either. Research backs its potential for weight management, insulin sensitivity, and possibly heart health yet it comes with trade-offs like hunger, nutrient gaps, and suitability concerns. As a dietitian, I’d say it’s a tool, not a rule. The best approach is the one you can sustain while nourishing your body. If Intermittent fasting fits your lifestyle and goals, give it a try. Just don’t skip the science (or your veggies).

 

 

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By Sarah Salomey Okine
Sarah Salomey Kailey Okine is a registered dietitian, quality assurance specialist, and product development consultant with a passion for nutrition, food safety, and wellness. She combines scientific expertise with practical solutions to help individuals and businesses optimize their approach to health and nutrition. She currently works as a Quality Assurance Specialist at Airways Catering Limited, ensuring high food safety and quality standards in the aviation catering industry. She also serves as a Dietitian at Violet Medical Center, providing personalized nutrition care to support patients in managing various health conditions. As the founder of Diet Right Clinical Consult, she continues to guide individuals on their weight management and wellness journeys. She is also the creator of Nutty Nibbs, a granola brand designed to support overall health and skin nourishment. Her mission is to make nutrition simple, accessible, and impactful—whether through individualized care, food safety assurance, or product innovation.
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